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Frozen section slides demonstrating bland, variably sized vascular proliferations within a paucicellular, sclerotic background. (A) Low-power view (4× magnification). (B) Higher-power view (10× magnification). (C) Microscopic examination of the surgical resection shows lesional tissue composed of a proliferation of ectatic and congested vessels with prominent hyalinization (10x magnification). (D) An immunostain for CD34 highlights a flattened single layer of vascular endothelium. These findings are consistent with a cavernous <t>malformation.</t>
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Frozen section slides demonstrating bland, variably sized vascular proliferations within a paucicellular, sclerotic background. (A) Low-power view (4× magnification). (B) Higher-power view (10× magnification). (C) Microscopic examination of the surgical resection shows lesional tissue composed of a proliferation of ectatic and congested vessels with prominent hyalinization (10x magnification). (D) An immunostain for CD34 highlights a flattened single layer of vascular endothelium. These findings are consistent with a cavernous <t>malformation.</t>
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Frozen section slides demonstrating bland, variably sized vascular proliferations within a paucicellular, sclerotic background. (A) Low-power view (4× magnification). (B) Higher-power view (10× magnification). (C) Microscopic examination of the surgical resection shows lesional tissue composed of a proliferation of ectatic and congested vessels with prominent hyalinization (10x magnification). (D) An immunostain for CD34 highlights a flattened single layer of vascular endothelium. These findings are consistent with a cavernous malformation.

Journal: Radiology Case Reports

Article Title: Posterior fossa cavernous malformation mimicking meningioma: A case report

doi: 10.1016/j.radcr.2026.04.001

Figure Lengend Snippet: Frozen section slides demonstrating bland, variably sized vascular proliferations within a paucicellular, sclerotic background. (A) Low-power view (4× magnification). (B) Higher-power view (10× magnification). (C) Microscopic examination of the surgical resection shows lesional tissue composed of a proliferation of ectatic and congested vessels with prominent hyalinization (10x magnification). (D) An immunostain for CD34 highlights a flattened single layer of vascular endothelium. These findings are consistent with a cavernous malformation.

Article Snippet: Given the multifocal nature of these lesions, the patient underwent an Invitae Cerebral Cavernous Malformation genetic panel, which assessed the CCM2, KRIT1, and PDCD10 genes associated with familial CM; the results were negative.

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